3FRB
S. aureus F98Y DHFR complexed with TMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | X | Dihydrofolate reductase | polymer | 158 | 18160.7 | 1 | UniProt (P0A017) Pfam (PF00186) In PDB | Staphylococcus aureus | DHFR |
| 2 | X | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 3 | X | TRIMETHOPRIM | non-polymer | 290.3 | 1 | Chemie (TOP) | |||
| 4 | water | water | 18.0 | 121 | Chemie (HOH) |
Sequence modifications
X: 1 - 158 (UniProt: P0A017)
| PDB | External Database | Details |
|---|---|---|
| Tyr 98 | Phe 99 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18160.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1033.7 | |
| All* | Total formula weight | 19194.5 |
