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3FQZ

Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3-methoxy-4-phenylphenyl)but-1-ynyl]-6-methylpyrimidine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Trimethoprim-sensitive dihydrofolate reductasepolymer15718015.61UniProt (Q2YY41)Staphylococcus aureus RF122
2B
(A)
5-[(3S)-3-(2-methoxybiphenyl-4-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diaminenon-polymer358.41Chemie (11F)
3C
(A)
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.41Chemie (NDP)
4D
(A)
waterwater18.0131Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight18015.6
Non-Polymers*Number of molecules2
Total formula weight1103.9
All*Total formula weight19119.4
*Water molecules are not included.

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PDB entries from 2025-07-23

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