3FQL
Hepatitis C virus polymerase NS5B (CON1 1-570) with HCV-796 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RNA-directed RNA polymerase | polymer | 578 | 64389.9 | 1 | UniProt (Q9WMX2) Pfam (PF00998) | Hepatitis C virus (HCV) | |
| 2 | B (A) | 5-cyclopropyl-2-(4-fluorophenyl)-6-[(2-hydroxyethyl)(methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide | non-polymer | 446.5 | 1 | Chemie (79Z) | |||
| 3 | C, D (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | E (A) | water | water | 18.0 | 369 | Chemie (HOH) |
Sequence modifications
A: 2 - 570 (UniProt: Q9WMX2)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | expression tag |
| Ala -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Met -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 64389.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 630.7 | |
| All* | Total formula weight | 65020.6 |
