3FQL

Hepatitis C virus polymerase NS5B (CON1 1-570) with HCV-796 inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	RNA-directed RNA polymerase	polymer	578	64389.9	1	UniProt (Q9WMX2) Pfam (PF00998) In PDB	Hepatitis C virus (HCV)
2	A	5-cyclopropyl-2-(4-fluorophenyl)-6-[(2-hydroxyethyl)(methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide	non-polymer		446.5	1	Chemie (79Z)
3	A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4		water	water		18.0	369	Chemie (HOH)

Sequence modifications

A: 2 - 570 (UniProt: Q9WMX2)

PDB	External Database	Details
Met -7	-	expression tag
Ala -6	-	expression tag
Ser -5	-	expression tag
Met -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	64389.9
Non-Polymers*	Number of molecules	3
	Total formula weight	630.7
All*	Total formula weight	65020.6

*Water molecules are not included.