3FQC
Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3,4,5-trimethoxyphenyl)pent-1-ynyl]-6-methylpyrimidine (UCP115A)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Trimethoprim-sensitive dihydrofolate reductase | polymer | 157 | 18015.6 | 2 | UniProt (Q2YY41) | Staphylococcus aureus RF122 | |
| 2 | C, E (A, B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | D, F (A, B) | 6-methyl-5-[3-methyl-3-(3,4,5-trimethoxyphenyl)but-1-yn-1-yl]pyrimidine-2,4-diamine | non-polymer | 356.4 | 2 | Chemie (55V) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36031.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2203.7 | |
| All* | Total formula weight | 38234.8 |
