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3FQC

Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3,4,5-trimethoxyphenyl)pent-1-ynyl]-6-methylpyrimidine (UCP115A)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BTrimethoprim-sensitive dihydrofolate reductasepolymer15718015.62UniProt (Q2YY41)
In PDB
Staphylococcus aureus RF122
2A, BNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.42Chemie (NDP)
3A, B6-methyl-5-[3-methyl-3-(3,4,5-trimethoxyphenyl)but-1-yn-1-yl]pyrimidine-2,4-diaminenon-polymer356.42Chemie (55V)
4waterwater18.0134Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight36031.1
Non-Polymers*Number of molecules4
Total formula weight2203.7
All*Total formula weight38234.8
*Water molecules are not included.

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PDB entries from 2024-05-15

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