3FQ0
Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120B)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Trimethoprim-sensitive dihydrofolate reductase | polymer | 157 | 18015.6 | 1 | UniProt (Q2YY41) | Staphylococcus aureus RF122 | |
2 | B (A) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
3 | C (A) | 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine | non-polymer | 312.4 | 1 | Chemie (N22) | |||
4 | D (A) | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 18015.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1057.8 | |
All* | Total formula weight | 19073.3 |