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3FQ0

Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120B)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Trimethoprim-sensitive dihydrofolate reductasepolymer15718015.61UniProt (Q2YY41)Staphylococcus aureus RF122
2B
(A)
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.41Chemie (NDP)
3C
(A)
5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diaminenon-polymer312.41Chemie (N22)
4D
(A)
waterwater18.0143Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight18015.6
Non-Polymers*Number of molecules2
Total formula weight1057.8
All*Total formula weight19073.3
*Water molecules are not included.

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PDB entries from 2024-10-30

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