3FKU
Crystal structure of influenza hemagglutinin (H5) in complex with a broadly neutralizing antibody F10
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E, G, I... | Hemagglutinin | polymer | 338 | 38466.6 | 6 | UniProt (Q6DQ33) Pfam (PF00509) UniProt (by SIFTS) (Q6J8F6) In PDB | Influenza A virus | Hemagglutinin HA1 chain |
2 | B, D, F, H, J... | Hemagglutinin | polymer | 182 | 20980.2 | 6 | UniProt (Q2F4V2) Pfam (PF00509) UniProt (by SIFTS) (Q6J8F6) In PDB | Influenza A virus | Hemagglutinin HA2 chain |
3 | X, Y, Z, S, T... | Neutralizing antibody F10 | polymer | 280 | 29280.2 | 6 | Homo sapiens (human) | ||
4 | a, c, M, O, Q... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
5 | b, d, N, P, R... | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 6 | In PDB GlyTouCan (G15407YE) |
Sequence modifications
A, C, E, G, I, K: 5 - 334 (UniProt: Q6DQ33)
B, D, F, H, J, L: 1 - 176 (UniProt: Q2F4V2)
PDB | External Database | Details |
---|---|---|
Ala -3 | - | expression tag |
Asp -2 | - | expression tag |
Pro -1 | - | expression tag |
Gly 0 | - | expression tag |
Tyr 1 | - | expression tag |
Leu 2 | - | expression tag |
Leu 3 | - | expression tag |
Glu 4 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Arg 177 | - | expression tag |
Ser 178 | - | expression tag |
Leu 179 | - | expression tag |
Val 180 | - | expression tag |
Pro 181 | - | expression tag |
Arg 182 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 18 |
Total formula weight | 532362.2 | |
Branched | Number of molecules | 12 |
Total formula weight | 6065.7 | |
All* | Total formula weight | 538427.9 |