3FK7
Crystal structure of TetR triple mutant (H64K, S135L, S138I) in complex with 4-ddma-atc
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Tetracycline repressor protein class B from transposon Tn10, Tetracycline repressor protein class D | polymer | 208 | 23448.8 | 2 | UniProt (P04483) UniProt (P0ACT4) Pfam (PF00440) Pfam (PF02909) In PDB | Escherichia coli | |
2 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
3 | A, B | (4aS,12aS)-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide | non-polymer | 383.4 | 2 | Chemie (4DM) | |||
4 | water | water | 18.0 | 225 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 50 (UniProt: P04483)
A, B: 51 - 208 (UniProt: P0ACT4)
A, B: 51 - 208 (UniProt: P0ACT4)
PDB | External Database | Details |
---|---|---|
Lys 64 | His 64 | engineered mutation |
Leu 135 | Ser 135 | engineered mutation |
Ile 138 | Ser 138 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 46897.6 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 815.3 | |
All* | Total formula weight | 47712.9 |