3FJN
The crystal structure of 17-alpha hydroxysteroid dehydrogenase Y224D mutant.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Aldo-keto reductase family 1 member C21 | polymer | 323 | 36876.5 | 2 | UniProt (Q91WR5) Pfam (PF00248) In PDB | Mus musculus (mouse) | 17-alpha-hydroxysteroid dehydrogenase, 17-alpha-HSD, 3-alpha-hydroxysteroid dehydrogenase, Dihydrodiol dehydrogenase type 1, DD1, Dihydrodiol dehydrogenase type 3, DD3 |
| 2 | A, B | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 3 | water | water | 18.0 | 513 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 323 (UniProt: Q91WR5)
| PDB | External Database | Details |
|---|---|---|
| Asp 224 | Tyr 224 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73753.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 236.2 | |
| All* | Total formula weight | 73989.2 |
