3FJE

Crystal structure of C83S mutant of Human acidic fibroblast growth factor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Heparin-binding growth factor 1	polymer	146	16670.7	2	UniProt (P05230) Pfam (PF00167) In PDB	Homo sapiens (human)	HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF-beta
2	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
3	A, B	FORMIC ACID	non-polymer		46.0	4	Chemie (FMT)
4		water	water		18.0	159	Chemie (HOH)

Sequence modifications

A, B: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
Ser 83	Cys 98	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33341.4
Non-Polymers*	Number of molecules	5
	Total formula weight	280.2
All*	Total formula weight	33621.5

*Water molecules are not included.