3FIG
Crystal Structure of Leucine-bound LeuA from Mycobacterium tuberculosis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 2-isopropylmalate synthase | polymer | 646 | 70285.5 | 2 | UniProt (P96420) Pfam (PF00682) Pfam (PF22615) Pfam (PF08502) UniProt (by SIFTS) (P9WQB3) | Mycobacterium tuberculosis | Alpha-isopropylmalate synthase, Alpha-IPM synthetase |
| 2 | C, F (A, B) | LEUCINE | non-polymer | 131.2 | 2 | Chemie (LEU) | |||
| 3 | D, G (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | E (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 366 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 644 (UniProt: P96420)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Ala 2 | Thr 2 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 140571.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 511.9 | |
| All* | Total formula weight | 141083.0 |
