3FEA
Crystal Structure of HdmX bound to the p53-peptidomimetic Ac-Phe-Met-Aib-Pmp-6-Cl-Trp-Glu-Ac3c-Leu-NH2 at 1.33A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Mdm4 protein | polymer | 100 | 11187.0 | 1 | UniProt (O15151) In PDB | Homo sapiens (Human) | p53-binding protein Mdm4, Mdm2-like p53-binding protein, Protein Mdmx, Double minute 4 protein |
| 2 | L, M | p53-peptidomimetic Ac-Phe-Met-Aib-Pmp-6-Cl-Trp-Glu-Ac3c-Leu-NH2 | polymer | 10 | 1192.7 | 2 | |||
| 3 | A | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 4 | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence modifications
A: 14 - 111 (UniProt: O15151)
| PDB | External Database | Details |
|---|---|---|
| Gly 12 | - | expression tag |
| Pro 13 | - | expression tag |
| Ser 17 | Cys 17 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 13572.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 118.2 | |
| All* | Total formula weight | 13690.6 |
