3FD7
Crystal structure of Onconase C87A/C104A-ONC
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protein P-30 | polymer | 104 | 11781.5 | 2 | UniProt (P22069) Pfam (PF00074) | Rana pipiens (Northern leopard frog) | Onconase |
| 2 | C, D, E, I, J... (A, B) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 3 | F, G, M (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | N, O (A, B) | water | water | 18.0 | 355 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 104 (UniProt: P22069)
| PDB | External Database | Details |
|---|---|---|
| Ala 87 | Cys 87 | engineered mutation |
| Ala 104 | Cys 104 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 23563.0 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1010.8 | |
| All* | Total formula weight | 24573.8 |
