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3FCU

Structure of headpiece of integrin aIIBb3 in open conformation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, EIntegrin, alpha 2bpolymer45749516.03UniProt (Q17R67)
Pfam (PF01839)
UniProt (by SIFTS) (P08514)
In PDB
Homo sapiens (human)
2B, D, FIntegrin beta-3polymer46150969.73UniProt (P05106)
Pfam (PF17205)
Pfam (PF00362)
Pfam (PF18372)
In PDB
Homo sapiens (human)Platelet membrane glycoprotein IIIa, GPIIIa
3G, Ialpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched910.82In PDB
GlyTouCan (G21381MC)
4Halpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched748.71In PDB
GlyTouCan (G48068RF)
5D, E, A, F, B...CALCIUM IONnon-polymer40.118Chemie (CA)
6D, E, A, F, B...2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.28Chemie (NAG)
7C, D, E, F, A...MAGNESIUM IONnon-polymer24.36Chemie (MG)
8D, F, BCACODYLATE IONnon-polymer137.03Chemie (CAC)
9waterwater18.0298Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight301456.9
BranchedNumber of molecules3
Total formula weight2570.3
Non-Polymers*Number of molecules35
Total formula weight3047.9
All*Total formula weight307075.1
*Water molecules are not included.

224004

PDB entries from 2024-08-21

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