3FCU
Structure of headpiece of integrin aIIBb3 in open conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Integrin, alpha 2b | polymer | 457 | 49516.0 | 3 | UniProt (Q17R67) Pfam (PF01839) UniProt (by SIFTS) (P08514) | Homo sapiens (human) | |
| 2 | B, D, F (B, D, F) | Integrin beta-3 | polymer | 461 | 50969.7 | 3 | UniProt (P05106) Pfam (PF17205) Pfam (PF00362) Pfam (PF18372) | Homo sapiens (human) | Platelet membrane glycoprotein IIIa, GPIIIa |
| 3 | G, I (G, I) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G21381MC) | |||
| 4 | H (H) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G48068RF) | |||
| 5 | CA, DA, HA, IA, J... (D, E, A, F, B...) | CALCIUM ION | non-polymer | 40.1 | 18 | Chemie (CA) | |||
| 6 | EA, FA, LA, N, QA... (D, E, A, F, B...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) | |||
| 7 | AA, BA, MA, NA, O... (C, D, E, F, A...) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 8 | GA, RA, U (D, F, B) | CACODYLATE ION | non-polymer | 137.0 | 3 | Chemie (CAC) | |||
| 9 | SA, TA, UA (A, C, E) | water | water | 18.0 | 298 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 301456.9 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 2570.3 | |
| Non-Polymers* | Number of molecules | 35 |
| Total formula weight | 3047.9 | |
| All* | Total formula weight | 307075.1 |
