3FC0

1.8 A crystal structure of murine GITR ligand dimer expressed in Drosophila melanogaster S2 cells

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	GITR ligand	polymer	139	15902.3	2	UniProt (Q7TS55) Pfam (PF00229)	Mus musculus (mouse)	Glucocorticoid-induced-tumor necrosis factor receptor ligand, Tumor necrosis factor (Ligand) superfamily, member 18
2	C (A)	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
3	D, E (A, B)	water	water		18.0	92	Chemie (HOH)

Sequence modifications

A, B: 46 - 173 (UniProt: Q7TS55)

PDB	External Database	Details
Arg 35	-	expression tag
Ser 36	-	expression tag
His 37	-	expression tag
His 38	-	expression tag
His 39	-	expression tag
His 40	-	expression tag
His 41	-	expression tag
His 42	-	expression tag
Ser 43	-	expression tag
Ser 44	-	expression tag
Gly 45	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	31804.6
Non-Polymers*	Number of molecules	1
	Total formula weight	59.0
All*	Total formula weight	31863.6

*Water molecules are not included.