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3FAS

X-ray structure of iGluR4 flip ligand-binding core (S1S2) in complex with (S)-glutamate at 1.40A resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Glutamate receptor 4polymer26029020.52UniProt (P19493)
Pfam (PF10613)
Pfam (PF00060)
Rattus norvegicus (RAT)ionotropic glutamate receptor 4, GluR-4, GluR4, GluR-D, Glutamate receptor ionotropic, AMPA 4, AMPA-selective glutamate receptor 4
2C, K
(A, B)
GLUTAMIC ACIDnon-polymer147.12Chemie (GLU)
3D, E, F, L, M...
(A, B)
SULFATE IONnon-polymer96.18Chemie (SO4)
4G, H, I, J, Q...
(A, B)
GLYCEROLnon-polymer92.19Chemie (GOL)
5V, W
(A, B)
waterwater18.0888Chemie (HOH)
Sequence modifications
A, B: 2 - 115 (UniProt: P19493)
PDBExternal DatabaseDetails
Gly 1-expression tag
A, B: 118 - 260 (UniProt: P19493)
PDBExternal DatabaseDetails
Gly 116-linker
Thr 117-linker
Ile 198Thr 734SEE REMARK 999
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight58041.1
Non-Polymers*Number of molecules19
Total formula weight1891.6
All*Total formula weight59932.7
*Water molecules are not included.

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PDB entries from 2025-06-25

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