3FAS

X-ray structure of iGluR4 flip ligand-binding core (S1S2) in complex with (S)-glutamate at 1.40A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Glutamate receptor 4	polymer	260	29020.5	2	UniProt (P19493) Pfam (PF10613) Pfam (PF00060) In PDB	Rattus norvegicus (RAT)	ionotropic glutamate receptor 4, GluR-4, GluR4, GluR-D, Glutamate receptor ionotropic, AMPA 4, AMPA-selective glutamate receptor 4
2	A, B	GLUTAMIC ACID	non-polymer		147.1	2	Chemie (GLU)
3	A, B	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)
4	A, B	GLYCEROL	non-polymer		92.1	9	Chemie (GOL)
5		water	water		18.0	888	Chemie (HOH)

Sequence modifications

A, B: 2 - 115 (UniProt: P19493)

PDB	External Database	Details
Gly 1	-	expression tag

A, B: 118 - 260 (UniProt: P19493)

PDB	External Database	Details
Gly 116	-	linker
Thr 117	-	linker
Ile 198	Thr 734	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58041.1
Non-Polymers*	Number of molecules	19
	Total formula weight	1891.6
All*	Total formula weight	59932.7

*Water molecules are not included.