3FAO

Crystal structure of S118A mutant 3CLSP of PRRSV

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Non-structural protein	polymer	213	21985.9	1	UniProt (A1E8J1) Pfam (PF05579)	Porcine respiratory and reproductive syndrome virus (PRRSV)	Proteinase, 3C like serine protease, 3CLSP
2	B (A)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
3	C (A)	water	water		18.0	115	Chemie (HOH)

Sequence modifications

A: 1 - 204 (UniProt: A1E8J1)

PDB	External Database	Details
Gly -8	-	expression tag
Pro -7	-	expression tag
Leu -6	-	expression tag
Gly -5	-	expression tag
Ser -4	-	expression tag
Pro -3	-	expression tag
Glu -2	-	expression tag
Phe -1	-	expression tag
Pro 0	-	expression tag
Ala 118	Ser 1897	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	21985.9
Non-Polymers*	Number of molecules	1
	Total formula weight	95.0
All*	Total formula weight	22080.9

*Water molecules are not included.