3F74
Crystal structure of wild type LFA1 I domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Integrin alpha-L | polymer | 181 | 20739.8 | 3 | UniProt (P20701) Pfam (PF00092) | Homo sapiens (Human) | Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, Leukocyte function-associated molecule 1 alpha chain, CD11 antigen-like family member A |
| 2 | D, E (B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 3 | F (C) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | G, H, I (A, B, C) | water | water | 18.0 | 708 | Chemie (HOH) |
Sequence modifications
A, B, C: 128 - 307 (UniProt: P20701)
| PDB | External Database | Details |
|---|---|---|
| Met 127 | - | expression tag |
| Trp 189 | Arg 214 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 62219.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 208.5 | |
| All* | Total formula weight | 62427.8 |
