3F74
Crystal structure of wild type LFA1 I domain
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 1 |
| Chain | Residue |
| B | GOL2 |
| B | GLY246 |
| B | ASN247 |
| B | HOH313 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 2 |
| Chain | Residue |
| B | GOL1 |
| B | SER245 |
| B | HOH319 |
| B | HOH594 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG C 1 |
| Chain | Residue |
| C | SER141 |
| C | ASP239 |
| C | HOH595 |
| C | SER139 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 513 |
| Details | Domain: {"description":"VWFA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00219","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15728350","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26936951","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T0P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E6R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E6S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E6U","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15728350","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26936951","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T0P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E6R","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26936951","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5E6R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E6S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E6U","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
