3F6Q
Crystal structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrin-linked protein kinase | polymer | 179 | 20256.9 | 1 | UniProt (Q13418) Pfam (PF12796) | Homo sapiens (Human) | ILK-1, ILK-2, 59 kDa serine/threonine-protein kinase, p59ILK |
| 2 | B (B) | LIM and senescent cell antigen-like-containing domain protein 1 | polymer | 72 | 8288.2 | 1 | UniProt (P48059) Pfam (PF00412) | Homo sapiens (Human) | Particularly interesting new Cys-His protein 1, PINCH-1, Renal carcinoma antigen NY-REN-48 |
| 3 | C, D, E, F, G... (A, B) | IODIDE ION | non-polymer | 126.9 | 18 | Chemie (IOD) | |||
| 4 | T (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | U, V (B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | X, Y (A, B) | water | water | 18.0 | 363 | Chemie (HOH) |
Sequence modifications
B: 6 - 68 (UniProt: P48059)
| PDB | External Database | Details |
|---|---|---|
| Ser -3 | - | expression tag |
| Glu -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Tyr 1 | - | expression tag |
| Phe 2 | - | expression tag |
| Gln 3 | - | expression tag |
| Gly 4 | - | expression tag |
| Ser 5 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28545.1 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 2510.1 | |
| All* | Total formula weight | 31055.1 |
