3F5X
CDK-2-Cyclin complex with indazole inhibitor 9 bound at its active site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Cell division protein kinase 2 | polymer | 298 | 33976.5 | 2 | UniProt (P24941) Pfam (PF00069) | Homo sapiens (human) | p33 protein kinase |
| 2 | B, D (B, D) | Cyclin-A2 | polymer | 256 | 29428.1 | 2 | UniProt (P20248) Pfam (PF00134) Pfam (PF02984) | Homo sapiens (human) | Cyclin-A |
| 3 | E, G (A, C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | F, H (A, C) | 4-{3-[7-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline | non-polymer | 423.5 | 2 | Chemie (EZV) | |||
| 5 | I (D) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 68 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 126809.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1127.3 | |
| All* | Total formula weight | 127936.4 |
