3F5P
Complex Structure of Insulin-like Growth Factor Receptor and 3-Cyanoquinoline Inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Insulin-like growth factor 1 receptor | polymer | 308 | 35342.1 | 16 | UniProt (P08069) Pfam (PF07714) | Homo sapiens (Human) | Insulin-like growth factor I receptor, IGF-I receptor, CD221 antigen |
| 2 | AA, BA, CA, DA, EA... (K, M, L, R, S...) | 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile | non-polymer | 553.1 | 16 | Chemie (741) | |||
| 3 | GA, HA, IA, JA, KA... (A, B, C, D, E...) | water | water | 18.0 | 166 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, M, L, R, S, T: 981 - 1286 (UniProt: P08069)
| PDB | External Database | Details |
|---|---|---|
| Gly 979 | - | expression tag |
| Ser 980 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 565474.3 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 8849.2 | |
| All* | Total formula weight | 574323.5 |
