3F4F

Crystal structure of dUT1p, a dUTPase from Saccharomyces cerevisiae

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Deoxyuridine 5'-triphosphate nucleotidohydrolase	polymer	167	17494.6	3	UniProt (P33317) Pfam (PF00692)	Saccharomyces cerevisiae	dUTPase, dUTP pyrophosphatase
2	D, F, I (A, B, C)	2'-DEOXYURIDINE 5'-MONOPHOSPHATE	non-polymer		308.2	3	Chemie (UMP)
3	E (A)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
4	G, H (B)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
5	J, K (C)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
6	L, M, N (A, B, C)	water	water		18.0	437	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 147 (UniProt: P33317)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	52483.9
Non-Polymers*	Number of molecules	8
	Total formula weight	1283.9
All*	Total formula weight	53767.8

*Water molecules are not included.