3F0B
Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-Diamino-5-[3-(3-methoxy-5-phenylphenyl)but-1-ynyl]-6-methylpyrimidine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | X | Trimethoprim-sensitive dihydrofolate reductase | polymer | 157 | 18015.6 | 1 | UniProt (Q2YY41) In PDB | Staphylococcus aureus RF122 | |
2 | X | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
3 | X | 5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine | non-polymer | 358.4 | 1 | Chemie (53R) | |||
4 | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 18015.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1103.9 | |
All* | Total formula weight | 19119.4 |