3EX7
The crystal structure of EJC in its transition state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E | Protein mago nashi homolog | polymer | 146 | 17189.6 | 2 | UniProt (P61326) Pfam (PF02792) In PDB | Homo sapiens (human) | |
2 | B, G | RNA-binding protein 8A | polymer | 126 | 14637.2 | 2 | UniProt (Q9Y5S9) Pfam (PF00076) In PDB | Homo sapiens (human) | RNA-binding motif protein 8A, Ribonucleoprotein RBM8A, RNA-binding protein Y14, Binder of OVCA1-1, BOV-1 |
3 | C, H | Eukaryotic initiation factor 4A-III | polymer | 413 | 47173.2 | 2 | UniProt (P38919) Pfam (PF00270) Pfam (PF00271) In PDB | Homo sapiens (human) | Eukaryotic translation initiation factor 4A isoform 3, ATP-dependent RNA helicase eIF4A-3, ATP-dependent RNA helicase DDX48, DEAD box protein 48, Eukaryotic initiation factor 4A-like NUK-34, Nuclear matrix protein 265, hNMP 265 |
4 | D, I | Protein CASC3 | polymer | 146 | 17275.1 | 2 | UniProt (O15234) Pfam (PF09405) In PDB | Homo sapiens (human) | Cancer susceptibility candidate gene 3 protein, Metastatic lymph node protein 51, Protein MLN 51, Protein barentsz, Btz |
5 | F, J | RNA (5'-R(*UP*UP*UP*UP*UP*U)-3') | polymer | 6 | 1792.0 | 2 | |||
6 | C, H | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
7 | C, H | ALUMINUM FLUORIDE | non-polymer | 84.0 | 2 | Chemie (AF3) | |||
8 | C, H | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
9 | water | water | 18.0 | 380 | Chemie (HOH) |
Sequence modifications
B, G: 51 - 174 (UniProt: Q9Y5S9)
C, H: 1 - 411 (UniProt: P38919)
PDB | External Database | Details |
---|---|---|
Leu 175 | - | expression tag |
Glu 176 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Leu 412 | - | expression tag |
Glu 413 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 10 |
Total formula weight | 196134.3 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1071.0 | |
All* | Total formula weight | 197205.2 |