3EW3

the 1:2 complex between a Nterminal elongated prolactin and the extra cellular domain of the rat prolactin receptor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Prolactin	polymer	203	23614.0	1	UniProt (P01236) Pfam (PF00103) In PDB	Homo sapiens (human)	PRL
2	B, C	Prolactin receptor	polymer	221	26033.1	2	UniProt (P05710) Pfam (PF09067) Pfam (PF00041) In PDB	Rattus norvegicus (rat)	PRL-R, Lactogen receptor

Sequence modifications

A: 15 - 199 (UniProt: P01236)

PDB	External Database	Details
Met -3	-	initiating methionine
Ala -2	-	SEE REMARK 999
Gln -1	-	SEE REMARK 999
His 0	-	SEE REMARK 999
Pro 1	-	SEE REMARK 999
Pro 2	-	SEE REMARK 999
Tyr 3	-	SEE REMARK 999
Cys 4	-	SEE REMARK 999
Arg 5	-	SEE REMARK 999
Asn 6	-	SEE REMARK 999
Gln 7	-	SEE REMARK 999
Pro 8	-	SEE REMARK 999
Gly 9	-	SEE REMARK 999
Lys 10	-	SEE REMARK 999
Cys 11	-	SEE REMARK 999
Gln 12	-	SEE REMARK 999
Ile 13	-	SEE REMARK 999
Pro 14	-	SEE REMARK 999

B, C: 1 - 210 (UniProt: P05710)

PDB	External Database	Details
Met 0	-	initiating methionine
Arg 211	-	expression tag
Ser 212	-	expression tag
Arg 213	-	expression tag
Ser 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag
His 217	-	expression tag
His 218	-	expression tag
His 219	-	expression tag
His 220	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	75680.2
All*	Total formula weight	75680.2

*Water molecules are not included.