3EVE

Crystal structure of GpppA complex of yellow fever virus methyltransferase and S-adenosyl-L-homocysteine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	RNA-directed RNA polymerase NS5	polymer	277	31290.8	1	UniProt (P03314) Pfam (PF01728)	Yellow fever virus
2	B (A)	GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE	non-polymer		772.4	1	Chemie (G3A) PubChem (135450590) PubChem (162789443) PubChem (136948342) PubChem (171037886)
3	C (A)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	1	Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (13792) PubChem (177678424) PubChem (189149) PubChem (439155) PubChem (25210495) PubChem (21125603) PubChem (44361184) PubChem (25203782) PubChem (46936206) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (57544532) PubChem (52224400) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (5284331) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (71170554) PubChem (13231890) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (164157219) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525)
4	D (A)	water	water		18.0	281	Chemie (HOH)

Sequence modifications

A: 1 - 266 (UniProt: P03314)

PDB	External Database	Details
Met 0	-	expression tag
Gly 267	-	expression tag
Ser 268	-	expression tag
Ser 269	-	expression tag
Ser 270	-	expression tag
His 271	-	expression tag
His 272	-	expression tag
His 273	-	expression tag
His 274	-	expression tag
His 275	-	expression tag
His 276	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	31290.8
Non-Polymers*	Number of molecules	2
	Total formula weight	1156.8
All*	Total formula weight	32447.6

*Water molecules are not included.