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3EU5

Crystal structure of FTase(ALPHA-subunit; BETA-subunit DELTA C10) in complex with BiotinGPP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphapolymer37744098.11UniProt (Q04631)
Pfam (PF01239)
In PDB
Rattus norvegicus (Rat)CAAX farnesyltransferase subunit alpha, Ras proteins prenyltransferase alpha, FTase-alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha
2BProtein farnesyltransferase subunit betapolymer42747749.31UniProt (Q02293)
Pfam (PF00432)
In PDB
Rattus norvegicus (Rat)FTase-beta, CAAX farnesyltransferase subunit beta, RAS proteins prenyltransferase beta
3BZINC IONnon-polymer65.41Chemie (ZN)
4B(2E,6E)-3,7-dimethyl-8-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)octa-2,6-dien-1-yl trihydrogen diphosphatenon-polymer555.51Chemie (GBO)
5waterwater18.0132Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight91847.5
Non-Polymers*Number of molecules2
Total formula weight620.9
All*Total formula weight92468.4
*Water molecules are not included.

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PDB entries from 2024-08-28

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