3ET2

Structure of PPARdelta with 3-[5-Methoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-propionic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Peroxisome proliferator-activated receptor delta	polymer	287	32939.2	2	UniProt (Q03181) Pfam (PF00104) In PDB	Homo sapiens (human)	PPAR-delta, PPAR- beta, Nuclear receptor subfamily 1 group C member 2, Nuclear hormone receptor 1, NUC1, NUCI
2	A, B	3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid	non-polymer		389.4	2	Chemie (ET1)
3	A	1-BUTANOL	non-polymer		74.1	3	Chemie (1BO)
4		water	water		18.0	372	Chemie (HOH)

Sequence modifications

A, B: 165 - 441 (UniProt: Q03181)

PDB	External Database	Details
Met 155	-	expression tag
Lys 156	-	expression tag
Lys 157	-	expression tag
Gly 158	-	expression tag
His 159	-	expression tag
His 160	-	expression tag
His 161	-	expression tag
His 162	-	expression tag
His 163	-	expression tag
His 164	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	65878.4
Non-Polymers*	Number of molecules	5
	Total formula weight	1001.2
All*	Total formula weight	66879.6

*Water molecules are not included.