3EQ1
The Crystal Structure of Human Porphobilinogen Deaminase at 2.8A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Porphobilinogen deaminase | polymer | 361 | 39353.9 | 2 | UniProt (P08397) Pfam (PF01379) Pfam (PF03900) | Homo sapiens (Human) | PBG-D, Pre-uroporphyrinogen synthase, Hydroxymethylbilane synthase, HMBS |
| 2 | C, G (A, B) | 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid | non-polymer | 420.4 | 2 | Chemie (DPM) | |||
| 3 | D, E, F, H, I... (A, B) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) |
Sequence modifications
A, B: 1 - 361 (UniProt: P08397)
| PDB | External Database | Details |
|---|---|---|
| Gln 167 | Arg 167 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 78707.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1513.3 | |
| All* | Total formula weight | 80221.2 |
