3EP6
Human AdoMetDC D174N mutant complexed with S-Adenosylmethionine methyl ester and no putrescine bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | S-adenosylmethionine decarboxylase beta chain | polymer | 67 | 7694.6 | 1 | UniProt (P17707) | Homo sapiens (human) | AdoMetDC, SamDC |
| 2 | B (A) | S-adenosylmethionine decarboxylase alpha chain | polymer | 260 | 29887.2 | 1 | UniProt (P17707) Pfam (PF01536) | Homo sapiens (Human) | AdoMetDC, SamDC |
| 3 | C (A) | PYRUVIC ACID | non-polymer | 88.1 | 1 | Chemie (PYR) | |||
| 4 | D (A) | S-ADENOSYLMETHIONINE METHYL ESTER | non-polymer | 414.5 | 1 | Chemie (SMM) | |||
| 5 | E, F (B, A) | water | water | 18.0 | 163 | Chemie (HOH) |
Sequence modifications
A: 69 - 328 (UniProt: P17707)
| PDB | External Database | Details |
|---|---|---|
| Asn 174 | Asp 174 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37581.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 502.5 | |
| All* | Total formula weight | 38084.4 |
