3EOB

Crystal structure the Fab fragment of Efalizumab in complex with LFA-1 I domain, Form II

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (L, A)	Efalizumab Fab fragment, light chain	polymer	214	23436.1	2		Homo sapiens
2	B, E (H, B)	Efalizumab Fab fragment, heavy chain	polymer	220	23751.6	2		Homo sapiens
3	C, F (I, J)	Integrin alpha-L	polymer	181	20678.7	2	UniProt (P20701) Pfam (PF00092)	Homo sapiens	Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, Leukocyte function-associated molecule 1 alpha chain, CD11 antigen-like family member A
4	G, H (I, J)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	135732.7
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	135863.6

*Water molecules are not included.