3EO2

Crystal structure of the RhoGEF domain of human neuroepithelial cell-transforming gene 1 protein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Neuroepithelial cell-transforming gene 1 protein	polymer	231	27072.0	1	UniProt (Q7Z628) Pfam (PF00621)	Homo sapiens (Human)	p65 Net1 proto-oncogene, Rho guanine nucleotide exchange factor 8
2	B (A)	UNKNOWN ATOM OR ION	non-polymer			1	Chemie (UNX)

Sequence modifications

A: 161 - 373 (UniProt: Q7Z628)

PDB	External Database	Details
Met 143	-	expression tag
His 144	-	expression tag
His 145	-	expression tag
His 146	-	expression tag
His 147	-	expression tag
His 148	-	expression tag
His 149	-	expression tag
Ser 150	-	expression tag
Ser 151	-	expression tag
Gly 152	-	expression tag
Arg 153	-	expression tag
Glu 154	-	expression tag
Asn 155	-	expression tag
Leu 156	-	expression tag
Tyr 157	-	expression tag
Phe 158	-	expression tag
Gln 159	-	expression tag
Gly 160	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	27072.0
Non-Polymers*	Number of molecules	1
	Total formula weight	0.0
All*	Total formula weight	27072.0

*Water molecules are not included.