3EJJ
Structure of M-CSF bound to the first three domains of FMS
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Colony stimulating factor-1 | polymer | 155 | 18194.3 | 2 | UniProt (Q3U395) Pfam (PF05337) UniProt (by SIFTS) (P07141) In PDB | Mus musculus (mouse) | |
2 | X | Macrophage colony-stimulating factor 1 receptor | polymer | 289 | 32052.2 | 1 | UniProt (P09581) Pfam (PF00047) In PDB | Mus musculus (mouse) | CSF-1-R, Fms proto-oncogene, c-fms |
3 | C, D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
4 | water | water | 18.0 | 654 | Chemie (HOH) |
Sequence modifications
A, B: 4 - 148 (UniProt: Q3U395)
X: 20 - 296 (UniProt: P09581)
PDB | External Database | Details |
---|---|---|
Ala 1 | - | expression tag |
Asp 2 | - | expression tag |
Pro 3 | - | expression tag |
His 149 | - | expression tag |
His 150 | - | expression tag |
His 151 | - | expression tag |
His 152 | - | expression tag |
His 153 | - | expression tag |
His 154 | - | expression tag |
His 155 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ala 17 | - | expression tag |
Asp 18 | - | expression tag |
Pro 19 | - | expression tag |
Glu 297 | - | expression tag |
Ser 298 | - | expression tag |
His 299 | - | expression tag |
His 300 | - | expression tag |
His 301 | - | expression tag |
His 302 | - | expression tag |
His 303 | - | expression tag |
His 304 | - | expression tag |
His 305 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 68440.9 | |
Branched | Number of molecules | 2 |
Total formula weight | 848.8 | |
All* | Total formula weight | 69289.7 |