3EJ1
CDK2/CyclinA complexed with a pyrazolopyridazine inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Cell division protein kinase 2 | polymer | 298 | 33976.5 | 2 | UniProt (P24941) Pfam (PF00069) In PDB | Homo sapiens (human) | p33 protein kinase |
2 | B, D | Cyclin-A2 | polymer | 260 | 29867.5 | 2 | UniProt (P20248) Pfam (PF00134) Pfam (PF02984) In PDB | Homo sapiens (human) | Cyclin-A |
3 | A, C | N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine | non-polymer | 252.3 | 2 | Chemie (5BP) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 127688.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 504.6 | |
All* | Total formula weight | 128192.6 |