3EID
CDK2/CyclinA complexed with a pyrazolopyridazine inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Cell division protein kinase 2 | polymer | 298 | 33976.5 | 2 | UniProt (P24941) Pfam (PF00069) | Homo sapiens (Human) | p33 protein kinase |
| 2 | B, D (B, D) | Cyclin-A2 | polymer | 260 | 29867.5 | 2 | UniProt (P20248) Pfam (PF00134) Pfam (PF02984) | Homo sapiens (Human) | Cyclin-A |
| 3 | E (A) | (2S)-1-(dimethylamino)-3-(4-{[4-(6-morpholin-4-ylpyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-yl]amino}phenoxy)propan-2-ol | non-polymer | 490.6 | 1 | Chemie (PO5) | |||
| 4 | F (D) | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 127688.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 490.6 | |
| All* | Total formula weight | 128178.6 |
