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3EGX

Crystal structure of the mammalian COPII-coat protein Sec23a/24a complexed with the SNARE protein Sec22b and bound to the transport signal sequence of the SNARE protein Bet1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Protein transport protein Sec23Apolymer76486178.41UniProt (Q15436)
Pfam (PF04810)
Pfam (PF04811)
Pfam (PF08033)
Pfam (PF04815)
Pfam (PF00626)
Homo sapiens (Human)SEC23-related protein A
2B
(B)
Protein transport protein Sec24Apolymer74884336.81UniProt (O95486)
Pfam (PF00626)
Pfam (PF04810)
Pfam (PF04811)
Pfam (PF08033)
Pfam (PF04815)
Homo sapiens (Human)SEC24-related protein A
3C
(C)
Vesicle-trafficking protein SEC22bpolymer15718031.61UniProt (O75396)
Pfam (PF13774)
Pfam (PF00957)
Homo sapiens (Human)SEC22 vesicle-trafficking protein homolog B, SEC22 vesicle-trafficking protein-like 1, ERS24, ERS-24
4D
(D)
9-residue synthetic peptide from SNARE protein Bet1polymer91001.01UniProt (by SIFTS) (O15155)
5E, F
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
Sequence modifications
B: 346 - 1093 (UniProt: O95486)
PDBExternal DatabaseDetails
Ala 1056Arg 1056conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight189547.9
Non-Polymers*Number of molecules2
Total formula weight130.8
All*Total formula weight189678.7
*Water molecules are not included.

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PDB entries from 2025-08-27

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