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3EGD

Crystal structure of the mammalian COPII-coat protein Sec23a/24a complexed with the SNARE protein Sec22 and bound to the transport signal sequence of vesicular stomatitis virus glycoprotein

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Protein transport protein Sec23Apolymer76486178.41UniProt (Q15436)
Pfam (PF04810)
Pfam (PF04811)
Pfam (PF08033)
Pfam (PF04815)
Pfam (PF00626)
Homo sapiens (Human)SEC23-related protein A
2B
(B)
Protein transport protein Sec24Apolymer74884336.81UniProt (O95486)
Pfam (PF00626)
Pfam (PF04810)
Pfam (PF04811)
Pfam (PF08033)
Pfam (PF04815)
Homo sapiens (Human)SEC24-related protein A
3C
(C)
Vesicle-trafficking protein SEC22bpolymer15718031.61UniProt (O75396)
Pfam (PF13774)
Pfam (PF00957)
Homo sapiens (Human)SEC22 vesicle-trafficking protein homolog B, SEC22 vesicle-trafficking protein-like 1, ERS24, ERS-24
4D
(D)
10 residue peptide from VSV glycoproteinpolymer101283.41UniProt (by SIFTS) (P03522)
5E, F
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
6G, H, I
(A, B, C)
waterwater18.0163Chemie (HOH)
Sequence modifications
B: 346 - 1093 (UniProt: O95486)
PDBExternal DatabaseDetails
Ala 1056Arg 1056conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight189830.3
Non-Polymers*Number of molecules2
Total formula weight130.8
All*Total formula weight189961.1
*Water molecules are not included.

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PDB entries from 2025-07-23

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