3EFQ

T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-714

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Farnesyl pyrophosphate synthase	polymer	390	44475.7	2	UniProt (Q86C09) Pfam (PF00348) In PDB	Trypanosoma brucei
2	A, B	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
3	A, B	1-(2,2-diphosphonoethyl)-3-(octyloxy)pyridinium	non-polymer		396.3	2	Chemie (714)
4		water	water		18.0	256	Chemie (HOH)

Sequence modifications

A, B: 1 - 367 (UniProt: Q86C09)

PDB	External Database	Details
Met -22	-	expression tag
Gly -21	-	expression tag
Ser -20	-	expression tag
Ser -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
Gly -10	-	expression tag
Leu -9	-	expression tag
Val -8	-	expression tag
Pro -7	-	expression tag
Arg -6	-	expression tag
Gly -5	-	expression tag
Ser -4	-	expression tag
His -3	-	expression tag
Met -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	88951.5
Non-Polymers*	Number of molecules	8
	Total formula weight	938.5
All*	Total formula weight	89890.0

*Water molecules are not included.