3EE0
Crystal Structure of the W215A/E217A Mutant of Human Thrombin (space group P2(1)2(1)2(1))
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Thrombin light chain | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) In PDB | Homo sapiens (human) | |
| 2 | B | Thrombin heavy chain | polymer | 259 | 29607.1 | 1 | UniProt (P00734) Pfam (PF00089) In PDB | Homo sapiens (human) |
Sequence modifications
B: 16 - 247 (UniProt: P00734)
| PDB | External Database | Details |
|---|---|---|
| Ala 215 | Trp 590 | engineered mutation |
| Ala 217 | Glu 592 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33703.6 | |
| All* | Total formula weight | 33703.6 |
