3ECN
Crystal structure of PDE8A catalytic domain in complex with IBMX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A | polymer | 338 | 39090.0 | 2 | UniProt (O60658) Pfam (PF00233) | Homo sapiens (Human) | |
| 2 | C, F (A, B) | 3-ISOBUTYL-1-METHYLXANTHINE | non-polymer | 222.2 | 2 | Chemie (IBM) | |||
| 3 | D, G (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 78180.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 623.9 | |
| All* | Total formula weight | 78804.0 |
