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3E94

Crystal structure of RXRalpha ligand binding domain in complex with tributyltin and a coactivator fragment

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Retinoic acid receptor RXR-alphapolymer24427269.51UniProt (P19793)
Pfam (PF00104)
Homo sapiens (human)Retinoid X receptor alpha, Nuclear receptor subfamily 2 group B member 1
2B
(B)
Nuclear receptor coactivator 2 peptidepolymer131579.91UniProt (Q15596)NCoA-2, Transcriptional intermediary factor 2
3C
(A)
tributylstannanylnon-polymer290.11Chemie (TBY)
4D
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
5E, F
(A, B)
waterwater18.0160Chemie (HOH)
Sequence modifications
A: 223 - 462 (UniProt: P19793)
PDBExternal DatabaseDetails
Gly 219-expression tag
Ser 220-expression tag
His 221-expression tag
Met 222-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight28849.4
Non-Polymers*Number of molecules2
Total formula weight349.1
All*Total formula weight29198.5
*Water molecules are not included.

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PDB entries from 2024-11-06

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