3E7S
Structure of bovine eNOS oxygenase domain with inhibitor AR-C95791
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nitric oxide synthase, endothelial | polymer | 431 | 48393.7 | 1 | UniProt (P29473) Pfam (PF02898) | Bos taurus (bovine) | NOS TYPE III, endothelial NOS, cNOS, eNOS, NOSIII, EC-NOS, Constitutive NOS |
| 2 | B (B) | Nitric oxide synthase, endothelial | polymer | 431 | 48497.7 | 1 | UniProt (P29473) Pfam (PF02898) | Bos taurus (bovine) | NOS TYPE III, endothelial NOS, cNOS, eNOS, NOSIII, EC-NOS, Constitutive NOS |
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D, G (A, B) | HEME C | non-polymer | 618.5 | 2 | Chemie (HEC) | |||
| 5 | E, F, H, I (A, B) | ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE | non-polymer | 263.3 | 4 | Chemie (AT2) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 167 | Chemie (HOH) |
Sequence modifications
A: 54 - 484 (UniProt: P29473)
B: 54 - 484 (UniProt: P29473)
| PDB | External Database | Details |
|---|---|---|
| Arg 97 | Cys 99 | SEE REMARK 999 |
| PDB | External Database | Details |
|---|---|---|
| Arg 97 | Cys 99 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 96891.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2355.8 | |
| All* | Total formula weight | 99247.1 |
