Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 903 |
| Chain | Residue |
| A | CYS93 |
| A | CYS98 |
| B | CYS93 |
| B | CYS98 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE HEC A 901 |
| Chain | Residue |
| A | SER353 |
| A | TRP355 |
| A | GLU360 |
| A | TRP446 |
| A | PHE472 |
| A | TYR474 |
| A | AT2904 |
| A | AT2905 |
| A | HOH914 |
| A | TRP177 |
| A | ARG182 |
| A | CYS183 |
| A | SER225 |
| A | PHE352 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE AT2 A 904 |
| Chain | Residue |
| A | PRO333 |
| A | TRP355 |
| A | GLU360 |
| A | TYR474 |
| A | HEC901 |
| A | AT2905 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE AT2 A 905 |
| Chain | Residue |
| A | LEU104 |
| A | ARG364 |
| A | ALA445 |
| A | TRP446 |
| A | HEC901 |
| A | AT2904 |
| B | TRP73 |
| B | PHE459 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HEC B 902 |
| Chain | Residue |
| B | TRP177 |
| B | ARG182 |
| B | CYS183 |
| B | SER225 |
| B | PHE352 |
| B | SER353 |
| B | TRP355 |
| B | MET357 |
| B | GLU360 |
| B | TRP446 |
| B | PHE472 |
| B | TYR474 |
| B | AT2906 |
| B | AT2907 |
| B | HOH926 |
| B | HOH995 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE AT2 B 906 |
| Chain | Residue |
| B | GLN246 |
| B | PRO333 |
| B | VAL335 |
| B | GLY354 |
| B | TRP355 |
| B | GLU360 |
| B | TYR474 |
| B | HEC902 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE AT2 B 907 |
| Chain | Residue |
| A | TRP73 |
| A | PHE459 |
| B | VAL103 |
| B | ARG364 |
| B | ALA445 |
| B | TRP446 |
| B | HEC902 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG182-TRP189 | |
| B | ARG182-TRP189 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P35228","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P29474","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"UniProtKB","id":"P29474","evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 3nos |
| Chain | Residue | Details |
| A | ARG186 | |
| A | CYS183 | |
| A | GLU360 | |
| A | TRP355 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 3nos |
| Chain | Residue | Details |
| B | ARG186 | |
| B | CYS183 | |
| B | GLU360 | |
| B | TRP355 | |
