3E7A
Crystal Structure of Protein Phosphatase-1 Bound to the natural toxin Nodularin-R
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | polymer | 299 | 34162.1 | 2 | UniProt (P62136) Pfam (PF16891) Pfam (PF00149) | Homo sapiens (Human) | PP-1A |
| 2 | C, D (C, D) | nodularin R | polymer | 5 | 844.0 | 2 | NOR (NOR00279) BIRD (PRD_000214) | Nodularia spumigena | |
| 3 | E, F, R, S (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 4 | G, H, I, J, K... (A, B) | IODIDE ION | non-polymer | 126.9 | 14 | Chemie (IOD) | |||
| 5 | AA, N, O, P (B, A) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 6 | DA, Q (B, A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | BA, CA (B) | AZIDE ION | non-polymer | 42.0 | 2 | Chemie (AZI) | |||
| 8 | EA, FA, GA, HA (A, B, C, D) | water | water | 18.0 | 682 | Chemie (HOH) |
Sequence modifications
A, B: 7 - 300 (UniProt: P62136)
| PDB | External Database | Details |
|---|---|---|
| Gly 2 | - | expression tag |
| His 3 | - | expression tag |
| Met 4 | - | expression tag |
| Gly 5 | - | expression tag |
| Ser 6 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 70012.3 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 2406.4 | |
| All* | Total formula weight | 72418.7 |
