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3E6O

Structure of murine INOS oxygenase domain with inhibitor AR-C124355

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Nitric oxide synthase, induciblepolymer43350121.02UniProt (P29477)
Pfam (PF02898)
Mus musculus (mouse)Inducible NO synthase, Inducible NOS, iNOS, NOS type II, Macrophage NOS, MAC-NOS
2C, F
(A, B)
PROTOPORPHYRIN IX CONTAINING FEnon-polymer616.52Chemie (HEM)
3D, G
(A, B)
5,6,7,8-TETRAHYDROBIOPTERINnon-polymer241.22Chemie (H4B)
4E, H
(A, B)
N-[2-(4-AMINO-5,8-DIFLUORO-1,2-DIHYDROQUINAZOLIN-2-YL)ETHYL]-3-FURAMIDEnon-polymer320.32Chemie (A55)
5I, J
(A, B)
waterwater18.0273Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight100241.9
Non-Polymers*Number of molecules6
Total formula weight2356.1
All*Total formula weight102598.0
*Water molecules are not included.

238895

PDB entries from 2025-07-16

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