3E3E

Human Thioredoxin Double Mutant C35S,C73R

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Thioredoxin	polymer	105	11788.5	2	UniProt (P10599) Pfam (PF00085)	Homo sapiens (Human)	Trx, ATL-derived factor, ADF, Surface-associated sulphydryl protein, SASP
2	C, D (A, B)	HEXAETHYLENE GLYCOL	non-polymer		282.3	2	Chemie (P6G)
3	E, F (A, B)	water	water		18.0	130	Chemie (HOH)

Sequence modifications

A, B: 1 - 105 (UniProt: P10599)

PDB	External Database	Details
Ser 35	Cys 35	engineered mutation
Arg 73	Cys 73	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	23576.9
Non-Polymers*	Number of molecules	2
	Total formula weight	564.7
All*	Total formula weight	24141.6

*Water molecules are not included.