3E30
Protein farnesyltransferase complexed with FPP and ethylene diamine inhibitor 4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | polymer | 377 | 44098.1 | 1 | UniProt (Q04631) Pfam (PF01239) | Rattus norvegicus (rat) | CAAX farnesyltransferase subunit alpha, Ras proteins prenyltransferase alpha, FTase-alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha |
| 2 | B (B) | Protein farnesyltransferase subunit beta | polymer | 437 | 48722.3 | 1 | UniProt (Q02293) Pfam (PF00432) | Rattus norvegicus (rat) | FTase-beta, CAAX farnesyltransferase subunit beta, RAS proteins prenyltransferase beta |
| 3 | C (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (B) | FARNESYL DIPHOSPHATE | non-polymer | 382.3 | 1 | Chemie (FPP) | |||
| 5 | E (B) | tert-butyl 4-({(2-{(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)[(1-methyl-1H-imidazol-4-yl)sulfonyl]amino}methyl)piperidine-1-carboxylate | non-polymer | 596.7 | 1 | Chemie (ED4) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 435 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 92820.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1044.5 | |
| All* | Total formula weight | 93864.9 |
