3DZH
Crystal structure of human CD38 extracellular domain, GTP complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | ADP-ribosyl cyclase 1 | polymer | 262 | 30380.4 | 2 | UniProt (P28907) Pfam (PF02267) In PDB | Homo sapiens | Cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, T10, CD38 antigen |
2 | A, B | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
3 | water | water | 18.0 | 378 | Chemie (HOH) |
Sequence modifications
A, B: 45 - 300 (UniProt: P28907)
PDB | External Database | Details |
---|---|---|
Lys 39 | - | expression tag |
Arg 40 | - | expression tag |
Glu 41 | - | expression tag |
Ala 42 | - | expression tag |
Glu 43 | - | expression tag |
Ala 44 | - | expression tag |
Thr 49 | Gln 49 | engineered mutation |
Asp 100 | Asn 100 | engineered mutation |
Asp 164 | Asn 164 | engineered mutation |
Asp 209 | Asn 209 | engineered mutation |
Asp 219 | Asn 219 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 60760.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1046.4 | |
All* | Total formula weight | 61807.1 |