3DYQ
human phosphodiestrase 9 (inhibited by omitting divalent cation) in complex with cGMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | polymer | 329 | 38862.9 | 2 | UniProt (O76083) Pfam (PF00233) | Homo sapiens (Human) | |
| 2 | C, D, F, G (A, B) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 3 | E (A) | CYCLIC GUANOSINE MONOPHOSPHATE | non-polymer | 345.2 | 1 | Chemie (PCG) | |||
| 4 | H (B) | 3-ISOBUTYL-1-METHYLXANTHINE | non-polymer | 222.2 | 1 | Chemie (IBM) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 238 | Chemie (HOH) |
Sequence modifications
A, B: 182 - 506 (UniProt: O76083)
| PDB | External Database | Details |
|---|---|---|
| Gly 178 | - | expression tag |
| Ser 179 | - | expression tag |
| His 180 | - | expression tag |
| Met 181 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 77725.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 659.4 | |
| All* | Total formula weight | 78385.3 |
