3DYQ
human phosphodiestrase 9 (inhibited by omitting divalent cation) in complex with cGMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | polymer | 329 | 38862.9 | 2 | UniProt (O76083) Pfam (PF00233) | Homo sapiens (Human) | |
| 2 | C, D, F, G (A, B) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) PubChem (923) | |||
| 3 | E (A) | CYCLIC GUANOSINE MONOPHOSPHATE | non-polymer | 345.2 | 1 | Chemie (PCG) PubChem (177270406) PubChem (136759845) PubChem (135398570) PubChem (135402012) PubChem (135415582) PubChem (135530416) PubChem (135566687) PubChem (135612771) PubChem (136122637) PubChem (136183234) PubChem (136183235) PubChem (136239427) PubChem (136268916) PubChem (136454903) PubChem (136454906) PubChem (136488083) PubChem (136488088) PubChem (136499047) PubChem (136678837) PubChem (137218937) PubChem (137234705) PubChem (137279777) PubChem (138399475) PubChem (164162904) | |||
| 4 | H (B) | 3-ISOBUTYL-1-METHYLXANTHINE | non-polymer | 222.2 | 1 | Chemie (IBM) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 238 | Chemie (HOH) |
Sequence modifications
A, B: 182 - 506 (UniProt: O76083)
| PDB | External Database | Details |
|---|---|---|
| Gly 178 | - | expression tag |
| Ser 179 | - | expression tag |
| His 180 | - | expression tag |
| Met 181 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 77725.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 659.4 | |
| All* | Total formula weight | 78385.3 |
