3DYH

T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-721

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Farnesyl pyrophosphate synthase	polymer	390	44475.7	2	UniProt (Q86C09) Pfam (PF00348)	Trypanosoma brucei
2	C, D, E, G, H... (A, B)	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
3	F, J (A, B)	3-butoxy-1-(2,2-diphosphonoethyl)pyridinium	non-polymer		340.2	2	Chemie (721)
4	K, L (A, B)	water	water		18.0	349	Chemie (HOH)

Sequence modifications

A, B: 1 - 367 (UniProt: Q86C09)

PDB	External Database	Details
Met -22	-	expression tag
Gly -21	-	expression tag
Ser -20	-	expression tag
Ser -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
Gly -10	-	expression tag
Leu -9	-	expression tag
Val -8	-	expression tag
Pro -7	-	expression tag
Arg -6	-	expression tag
Gly -5	-	expression tag
Ser -4	-	expression tag
His -3	-	expression tag
Met -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	88951.5
Non-Polymers*	Number of molecules	8
	Total formula weight	826.3
All*	Total formula weight	89777.8

*Water molecules are not included.